Neuroscience

Analysis of brain organs and neuronal tissues to understand their physiological, pathological and toxicological homeostasis and devise pharmacological solutions to neuronal diseases

The research activities of this scope focus their efforts on the nervous system at several levels: organ, tissue, microenvironment and single cells, with molecular physiology approaches, as well as metabolomics, transcriptomics and biochemistry. This study develops and employs models to understand the functioning of neuronal systems in physiological conditions or in the presence of genetic disorders and pathological conditions, focusing on the development of new strategies to deal with neurodegenerative and metabolic diseases.

The development of new drugs to slow down and stop such diseases implements several technologies from the fields of pharmaceutical chemistry and neuropharmacology, focusing also on increasing drug delivery efficiency to brain and neuronal targets.

People

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Monica Baiula

Senior assistant professor (fixed-term)

D cat. - technical, scientific and data processing area

keywords: Integrin, Drug discovery, Inflammation, Molecular Pharmacology
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Federica Belluti

Associate Professor

keywords: natural products, multititarget drug discovery, design and synthesis of small molecules, antineurodegenetive small

Christian Bergamini

Associate Professor

keywords: Mitochondria, Mitochondrial electron transfer chain, Reactive Oxygen Species, Coenzyme Q10

Roberto Bernardoni

Assistant professor

keywords: Animal models of molecular mechanisms related to the onset and progression of childhood neuroblastoma, autism spectrum
keywords: multitarget drug discovery, design and synthesis, neglected tropical diseases, prion diseases, Alzheimer's disease,
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Renato Brandimarti

Assistant professor

Laura Calzà

Full Professor

keywords: animal models, neural stem cells, neurotrophins, embryonic stem cell, neurotransmitter
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Gabriele Campana

Assistant professor

keywords: bile acid, neonatal stress, POMC, FXR, opioids
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Marco Caprini

Associate Professor

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Lucia Carboni

Associate Professor

keywords: peripheral biomarkers, Alzheimer's disease, drug discovery, mood disorders, nicotine dependence
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Marco Cirrincione

PhD Student

Teaching tutor

keywords: microsampling, miniaturised pretreatment, liquid chromatography, mass spectrometry, drugs of abuse

Cecilia Delprete

PhD Student

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Anna Maria Ghelli

Associate Professor

keywords: mitochondria, Leber's Hereditary Optic Neuropathy, apoptosis, complex I, OPA1, Dominant Optic Atrophy, cancer
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Federico Manuel Giorgi

Associate Professor

keywords: Bioinformatics, Transcriptomics, Gene Networks, Plant Biology, Cancer Biology, Genomics, Biostatistics
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Patrizia Hrelia

Full Professor

keywords: Toxicity, Neuroprotection, Chemoprevention, Pharmacogenetic, Preventive medicine, Cancer, Biomarkers
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Luisa Iommarini

Associate Professor

keywords: mitochondria, cancer, tumor, metabolism, hypoxia, oxidative phosphorylation
keywords: Neuroscience, Endocannabinoids, Gene expression, Opioid peptides, Drugs of abuse
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Francesca Massenzio

Junior assistant professor (fixed-term)

keywords: neurodegeneration, neuroinflammation, glia, neurons, drug screening, ALS, AGC1-deficiency
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Laura Mercolini

Associate Professor

keywords: Drugs of abuse, Anti-doping analysis, Therapeutic drug monitoring (TDM), Analysis of natural compounds, Liquid
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Barbara Monti

Associate Professor

keywords: neuroprotection, neurodegeneration, neuroinflammation, memory, microglia, glia-neuron interactions, molecular and
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Fabiana Morroni

Associate Professor

keywords: Alzheimer's disease, Bioactive compounds, Neuroprotection, Parkinson's disease, Neurodegeneration
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Moreno Paolini

Full Professor

keywords: Chemoprevention, Cocancerogenesis, Free radicals, Phytochemicals, Cytochrome P450
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Eleonora Poeta

Research fellow

Teaching tutor

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Cecilia Prata

Associate Professor

keywords: Nutraceuticals, Signal transduction, NAD(P)H oxidases, Reactive Oxygen Species (ROS), Aquaporins, Antioxidants
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Michele Protti

Junior assistant professor (fixed-term)

keywords: Analytical methods, Microsampling, Sample pretreatment, doping agents, Drugs of abuse, SNC drugs, Biological and

Patrizia Romualdi

Associate Professor

keywords: gene expression, neuropeptides, opioid peptides, neurodegeneration, addictive drugs
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Giusy Tespio

PhD Student

keywords: liquid chromatography, mass spectrometry, analytical method development, sample stability, microsampling, banned
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Elisa Uliassi

Junior assistant professor (fixed-term)

keywords: polypharmacology, multi-target-directed-ligand, neurodegenerative diseases, neglected tropical diseases
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Giampaolo Zuccheri

Assistant professor