Neuropsychopharmacology. Coordinators: Carboni/Rimondini

The Neuropsychopharmacology group investigates the neurobiological basis of psychiatric and neurological disorders

Research themes 

1) Neurobiology and pharmacology of neurodegenerative disorders (Alzheimer’s disease, Parkinson’s disease, developmental disorders) 

2) Neurobiology, pharmacology, and biomarkers of psychiatric disorders (major depressive disorder, anxiety, addiction, schizophrenia)  

3) Drug discovery in neuroscience 

Lab members  

Lucia Carboni  my web site write to me  

Roberto Rimondini web site write to me 

 

Internship projects

Investigations on models of neurological and psychiatric disorders for students in the degrees of Medical Biotechnology, Pharmaceutical Biotechnologies, Farmacia, Pharmacy, CTF, Scienze Farmaceutiche Applicate. 

Main publications

Carboni L, Ponzoni L, Braida D, Sala M, Gotti C, Zoli M. (2021) Altered mRNA Levels of Stress-Related Peptides in Mouse Hippocampus and Caudate-Putamen in Withdrawal after Long-Term Intermittent Exposure to Tobacco Smoke or Electronic Cigarette Vapour. Int J Mol Sci. 22:599. https://www.mdpi.com/1422-0067/22/2/599  

Gennaccaro L, Fuchs C, Loi M, Pizzo R, Alvente S, Berteotti C, Lupori L, Sagona G, Galvani G, Gurgone A, Raspanti A, Medici G, Tassinari M, Trazzi S, Ren E, Rimondini R, Pizzorusso T, Giovanna Z, Maurizio G, Elisabetta C. (2021) Age-Related Cognitive and Motor Decline in a Mouse Model of CDKL5 Deficiency Disorder is Associated with Increased Neuronal Senescence and Death. Aging Dis. 12:764-785 http://www.aginganddisease.org/EN/10.14336/AD.2020.0827  

Carboni L, Marchetti L, Lauria M, Gass P, Vollmayr B, Redfern A, Jones L, Razzoli M, Malki K, Begni V, Riva MA, Domenici E, Caberlotto L, Mathé AA. (2018) Cross-species evidence from human and rat brain transcriptome for growth factor signaling pathway dysregulation in major depression. Neuropsychopharmacology. 43:2134-2145. https://www.nature.com/articles/s41386-018-0117-6  

Carboni L, McCarthy DJ, Delafont B, Filosi M, Ivanchenko E, Ratti E, Learned SM, Alexander R, Domenici E. (2019) Biomarkers for response in major depression: comparing paroxetine and venlafaxine from two randomised placebo-controlled clinical studies. Transl Psychiatry. 9:182. https://www.nature.com/articles/s41398-019-0521-7  

Caberlotto L, Nguyen TP, Lauria M, Priami C, Rimondini R, Maioli S, Cedazo-Minguez A, Sita G, Morroni F, Corsi M, Carboni L. (2019) Cross-disease analysis of Alzheimer's disease and type-2 Diabetes highlights the role of autophagy in the pathophysiology of two highly comorbid diseases. Sci Rep. 9:3965. https://www.nature.com/articles/s41598-019-39828-5