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Department of Pharmacy and Biotechnology - FABIT

Pharmacogenetics and Pharmacogenomics. Coordinator: Angelini

The mission of the research group is the identification of genetic and epigenetic profiles of response to drug treatment in patients with chronic degenerative diseases.

Areas: Drug discovery and development Genomics Nutrition and health

Research Themes

The mission of the research group is the identification of genetic and epigenetic profiles of response to drug treatment in patients with chronic degenerative diseases 

Lab Members

Sabrina Angelini, Professoressa Associata

Francesca Gorini, Dottoranda

Emma Coschina, Dottoranda

Internship projects

Possibility to endorse experimental theses for undergraduates.  

Internships for graduates or PhD students who want to implement their doctoral project thanks to an internship at our laboratories. PostDoc and researchers do not hesitate to contact us for collaborations and / or internships 

Main Publications

  • Catellani C, Ravegnini G, Sartori C, Righi B, Lazzeroni P, Bonvicini L, Poluzzi S, Cirillo F, Predieri B, Iughetti L, Giorgi Rossi P, Angelini S, Street ME (2022). “Specific miRNAs Change After 3 Months of GH treatment and Contribute to Explain the Growth Response After 12 Months.” Front Endocrinol. Jun 22;13:896640. PMID: 35813630  
  • Razmi, M., Yazdanpanah, A., Etemad-Moghdam, S., Alaeddini, M., Angelini, S., Eni, L. (2022). “Clinical prognostic value of the SMYD2/3 as new epigentic biomarkers in solid cancer patients: a systematic review and meta-analysis. Expert Rev Mol Diagn. Nov 17; 1-15. PMID: 36346387 https://doi.org/10.1080/14737159.2022.2144235 
  • Ravegnini, G., Fosso, B., Ricci, R., Gorini, F., Turroni, S., Serrano, C., Pilco-Janeta, D.F., Zhang, Q., Zanotti, F., De Robertis, M., Nannini, M., Pantaleo, M.A., Hrelia, P., Angelini, S. (2022). “Analysis of microbiome in gastrointestinal stromal tumors: Looking for different players in tumorigenesis and novel therapeutic options.” Cancer Sci, 113(8):2590-2599. http://dx.doi.org/10.1111/cas.15441. 
  • Ravegnini, G., Gorini, F., De Crescenzo, E., De Leo, A., De Biase, D., Di Stanislao, M., Hrelia, P., Angelini, S., De iaco, P., Perrone, A.M. (2022). “Can miRNAs be useful biomarkers in improving prognostic stratification in endometrial cancer patients? An update review. Int J Cancer, 150(7):1077-1090. https://doi.org/10.1002/ijc.33857. 
  • Ravegnini, G., De Leo, A., Coada, C., Gorini, F., de Biase, D., Ceccarelli, C., Dondi, G., Tesei, M., De Crescenzo, E., Santini, D., Corradini, A.G., Tallini, G., Hrelia, P., De Iaco, P., Angelini, S., Perrone, A.M. (2021). “Identification of miR-499a-5p as a Potential Novel Biomarker for Risk Stratification in Endometrial Cancer.” Front Oncol, 11:757678. http://dx.doi.org/10.3389/fonc.2021.757678. 

Contacts