Genomics

Development of experimental and bioinformatical methods to sequence, analyze and functionally understand prokaryotic and eukaryotic genomes

This scope studies prokaryotic and eukaryotic genomes to understand their architecture and dynamic functionality. Genomics naturally extends to the study of expressed gene transcripts (Transcriptomics) and to the active chromatin modifications (Epigenomics) to unveil the mechanisms by which genomes respond to stimuli in different histological tissues and pathological conditions. Human Genomics studies somatic mutations causally linked to cancer, germline polymorphisms linked to genetic diseases and mutations cause by the exposition to external mutagens (Toxicogenomics). In prokaryotes, the department research activities focus on the study of human pathogens and of novel bacterial species able to synthesize novel molecules with industrial and pharmaceutical applications.

People

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Giulia Babbi

Junior assistant professor (fixed-term)

keywords: Proteomics, Database development, Protein annotation, Gene-Disease relation, Rare diseases, Machine learning, Genomics,

Roberto Bernardoni

Assistant professor

keywords: Animal models of molecular mechanisms related to the onset and progression of childhood neuroblastoma, autism spectrum
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Renato Brandimarti

Assistant professor

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Marco Candela

Full Professor

keywords: Microbiome science, Metagenomics, Microbiome biotechnologies, One Health, Susteinabiulity, Microbial ecology and
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Martina Cappelletti

Associate Professor

keywords: Molecular microbiology, Microbial biotechnology, Microbial genomics, Omics applied to microbiology, Enviornmental
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Giovanni Capranico

Full Professor

keywords: DNA topoisomerases, R-loop and non-B DNA structures, Non-coding RNAs, Espressione genica, Transcription regulation,
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Emidio Capriotti

Associate Professor

keywords: Analysis and interpretation of cancer genome., Genome interpretation and prediction of disease-related protein

Fabiola Ceroni

Junior assistant professor (fixed-term)

keywords: autism, neurodevelopment, neuroscience
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Paolo Emidio Costantini

Research fellow

Teaching tutor

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Marco Fabbrini

PhD Student

keywords: Microbiome, Metagenomics, Microbiota
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Fabrizio Ferrè

Associate Professor

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Giorgio Gallinella

Full Professor

keywords: Parvovirus B19, Virus-cell interaction, Viral infections, Recombinant virus, Antiviral compounds
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Federico Manuel Giorgi

Associate Professor

keywords: Bioinformatics, Transcriptomics, Gene Networks, Plant Biology, Cancer Biology, Genomics, Biostatistics

Davide Maestri

PhD Student

Research fellow

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Jessica Marinello

Associate Professor

keywords: Human Topoisomerases, R-loops, Non canonical DNA structures, G-quadruplex, DNA damage

Laura Menotti

Associate Professor

keywords: viral vectors, oncolytic virotherapy, HER2 receptor, tumor-specific receptors, viral retargeting ad detargeting, herpes
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Daniele Mercatelli

Junior assistant professor (fixed-term)

keywords: Bioinformatics, Transcriptomics, Gene Networks, Genomics, Oncology, Biostatistics, Radiomics
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Giulia Miglietta

Research fellow

Teaching tutor

keywords: DNA secondary structure, G4 quadruplex, genome instability, DNA damage
keywords: bacterial pathogenesis
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Simone Rampelli

Junior assistant professor (fixed-term)

keywords: Microbiome, Metagenomics, Microbiota, Microbial Evolution

Patrizia Romualdi

Associate Professor

keywords: gene expression, neuropeptides, opioid peptides, neurodegeneration, addictive drugs
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Davide Roncarati

Associate Professor

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Marco Russo

Research fellow

keywords: Bioinformatics, DRIP-sequencng, RNA-sequencing, DNA secondary structures, G-quadrplexes, R-loop, Genome instability
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Vincenzo Scarlato

Full Professor

keywords: Transcriptome, Protein-DNA Interactions, Transcriptional regulation, Functional genomics, Drug discovery
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Roberto Tonelli

Assistant professor

keywords: Pharmaceutical Biotechnology, Preclinical Molecular Pharmacology, Oncology
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Maria Paola Turina

Assistant professor

keywords: ATP synthase, proton transport, electron tranfer, photosynthetic Reaction Center

Silvia Turroni

Associate Professor

keywords: Molecular biotechnology of phages- Development of theranostic vectors- Gene expression regulation in cancer- Molecular