Genomics

Development of experimental and bioinformatical methods to sequence, analyze and functionally understand prokaryotic and eukaryotic genomes

This scope studies prokaryotic and eukaryotic genomes to understand their architecture and dynamic functionality. Genomics naturally extends to the study of expressed gene transcripts (Transcriptomics) and to the active chromatin modifications (Epigenomics) to unveil the mechanisms by which genomes respond to stimuli in different histological tissues and pathological conditions. Human Genomics studies somatic mutations causally linked to cancer, germline polymorphisms linked to genetic diseases and mutations cause by the exposition to external mutagens (Toxicogenomics). In prokaryotes, the department research activities focus on the study of human pathogens and of novel bacterial species able to synthesize novel molecules with industrial and pharmaceutical applications.

Research groups

People

Giulia Babbi

Junior assistant professor (fixed-term)

keywords: Proteomics, Database development, Protein annotation, Gene-Disease relation, Rare diseases, Machine learning, Genomics,

Roberto Bernardoni

Assistant professor

keywords: Animal models of molecular mechanisms related to the onset and progression of childhood neuroblastoma, autism spectrum

Federica Bichicchi

PhD Student

Renato Brandimarti

Assistant professor

Marco Candela

Full Professor

keywords: Microbiome science, Metagenomics, Microbiome biotechnologies, One Health, Susteinabiulity, Microbial ecology and

Martina Cappelletti

Associate Professor

keywords: Molecular microbiology, Microbial biotechnology, Microbial genomics, Omics applied to microbiology, Enviornmental

Giovanni Capranico

Full Professor

keywords: DNA topoisomerases, R-loop and non-B DNA structures, Non-coding RNAs, Espressione genica, Transcription regulation,

Emidio Capriotti

Associate Professor

keywords: Analysis and interpretation of cancer genome., Genome interpretation and prediction of disease-related protein

Giacomo Cavalca

PhD Student

keywords: Data science, Artificial intelligence, Machine learning, Deep learning, Bioinformatics

Paolo Emidio Costantini

Research fellow

Teaching tutor

Fabrizio Ferrè

Associate Professor

Giorgio Gallinella

Full Professor

keywords: Parvovirus B19, Virus-cell interaction, Viral infections, Recombinant virus, Antiviral compounds

Federico Manuel Giorgi

Associate Professor

keywords: Bioinformatics, Transcriptomics, Gene Networks, Plant Biology, Cancer Biology, Genomics, Biostatistics

Jessica Marinello

Associate Professor

keywords: Human Topoisomerases, R-loops, Non canonical DNA structures, G-quadruplex, DNA damage

Laura Menotti

Associate Professor

keywords: viral vectors, oncolytic virotherapy, HER2 receptor, tumor-specific receptors, viral retargeting ad detargeting, herpes

Giorgio Milazzo

Senior assistant professor (fixed-term)

keywords: Genetics, Molecular Biology, Cancer Biology, Neuroblastoma

Marco Rinaldo Oggioni

Full Professor

keywords: bacterial pathogenesis

Simone Rampelli

Junior assistant professor (fixed-term)

keywords: Microbiome, Metagenomics, Microbiota, Microbial Evolution

Patrizia Romualdi

Full Professor

keywords: gene expression, neuropeptides, opioid peptides, neurodegeneration, addictive drugs

Davide Roncarati

Associate Professor

Marco Russo

Research fellow

Teaching tutor

keywords: Bioinformatics, DNA secondary structures, Genome instability, R-loop, G-quadruplex

Genomics

Research groups

People

Giulia Babbi

Roberto Bernardoni

Federica Bichicchi

Renato Brandimarti

Marco Candela

Martina Cappelletti

Giovanni Capranico

Emidio Capriotti

Giacomo Cavalca

Paolo Emidio Costantini

Fabrizio Ferrè

Giorgio Gallinella

Federico Manuel Giorgi

Jessica Marinello

Laura Menotti

Giorgio Milazzo

Marco Rinaldo Oggioni

Simone Rampelli

Patrizia Romualdi

Davide Roncarati

Marco Russo

Vincenzo Scarlato

Roberto Tonelli

Maria Paola Turina

Silvia Turroni

Suleman Khan Zadran