Cancer biology

Development and application of cell and molecular biology, genetics, biochemistry and nanotechnology to understand tumorigenesis and tumor progression

Cancer is a highly heterogeneous disease stemming from normal cells acquiring aberrant features, such as hyperproliferation, immunoevasion and deregulated cellular energetics.

The research activities in Cancer Biology employ several approaches to investigate the causes of this aberrant acquisition, using experiments and approaches both computational, genetical and molecular. Further screening of cancer cells is performed using data acquisition of biochemical, metabolic and transcriptional features. This scope aims also at understanding the action of pathogenic organisms (viruses and bacteria) with oncogenic properties and, more in general, focuses on the identification of novel anti-cancer molecular targets and innovational therapeutic strategies.

People

foto della persona

Giulia Babbi

Junior assistant professor (fixed-term)

keywords: Proteomics, Database development, Protein annotation, Gene-Disease relation, Rare diseases, Machine learning, Genomics,
foto della persona

Monica Baiula

Senior assistant professor (fixed-term)

Area dei Funzionari - Settore scientifico - tecnologico

keywords: Integrin, Drug discovery, Inflammation, Molecular Pharmacology
foto della persona

Federica Belluti

Associate Professor

keywords: natural products, multititarget drug discovery, design and synthesis of small molecules, antineurodegenetive small

Christian Bergamini

Associate Professor

keywords: Mitochondria, Mitochondrial electron transfer chain, Reactive Oxygen Species, Coenzyme Q10

Roberto Bernardoni

Assistant professor

keywords: Animal models of molecular mechanisms related to the onset and progression of childhood neuroblastoma, autism spectrum

Fabrizio Bertolazzi

PhD Student

Research fellow

foto della persona

Renato Brandimarti

Assistant professor

foto della persona

Concettina Cappadone

Assistant professor

keywords: magnesium, biomineralization, cancer, cell cycle, MDR
foto della persona

Giovanni Capranico

Full Professor

keywords: DNA topoisomerases, R-loop and non-B DNA structures, Non-coding RNAs, Espressione genica, Transcription regulation,
foto della persona

Emidio Capriotti

Associate Professor

keywords: Analysis and interpretation of cancer genome., Genome interpretation and prediction of disease-related protein
foto della persona

Giacomo Cavalca

PhD Student

keywords: Data science, Artificial intelligence, Machine learning, Deep learning, Bioinformatics
keywords: Bioinorganic Chemistry, Biomodelling, Biomolecular NMR spectroscopy, Metallo-chaperons, Urease, X-ray absorption
foto della persona

Dario De Biase

Associate Professor

keywords: Molecular Pathology, Molecular alterations of solid tumors, Next Generation Sequencing, Tumors
foto della persona

Giovanna Farruggia

Assistant professor

keywords: fluorescece spectroscopy, flow cytometry, magnesium, fluorescent dye, cell proliferation
foto della persona

Anna Maria Ghelli

Associate Professor

keywords: mitochondria, Leber's Hereditary Optic Neuropathy, apoptosis, complex I, OPA1, Dominant Optic Atrophy, cancer
foto della persona

Federico Manuel Giorgi

Associate Professor

keywords: Bioinformatics, Transcriptomics, Gene Networks, Plant Biology, Cancer Biology, Genomics, Biostatistics
foto della persona

Luca Grillini

PhD Student

Research fellow

foto della persona

Luisa Iommarini

Associate Professor

keywords: mitochondria, cancer, tumor, metabolism, hypoxia, oxidative phosphorylation
foto della persona

Stefano Iotti

Full Professor

keywords: fluorescent dyes, Magnesium, Biosensors, hydroxyquinoline derivatives, Synchreotron-based x-ray microscopy, magnetic

Emil Malucelli

Associate Professor

foto della persona

Jessica Marinello

Associate Professor

keywords: Human Topoisomerases, R-loops, Non canonical DNA structures, G-quadruplex, DNA damage
foto della persona

Luca Mazzei

Fixed-term Researcher in Tenure Track L. 79/2022

Laura Menotti

Associate Professor

keywords: viral vectors, oncolytic virotherapy, HER2 receptor, tumor-specific receptors, viral retargeting ad detargeting, herpes
foto della persona

Emanuela Mensà

Research fellow

foto della persona

Giorgio Milazzo

Senior assistant professor (fixed-term)

keywords: Genetics, Molecular Biology, Cancer Biology, Neuroblastoma
foto della persona

Francesco Musiani

Associate Professor

Simona Pepe

Research fellow

Teaching tutor

foto della persona

Laura Poppi

PhD Student

Teaching tutor

foto della persona

Cecilia Prata

Associate Professor

keywords: Nutraceuticals, Signal transduction, NAD(P)H oxidases, Reactive Oxygen Species (ROS), Aquaporins, Antioxidants
foto della persona

Marco Russo

Adjunct professor

Research fellow

Teaching tutor

keywords: Bioinformatics, DNA secondary structures, Genome instability, R-loop, G-quadruplex
foto della persona

Manuela Sollazzo

Junior assistant professor (fixed-term)

keywords: cancer; metabolism; Respiratory Complex I; pro-tumorigenic signaling cascades; Drosophila melanogaster
foto della persona

Roberto Tonelli

Assistant professor

keywords: Pharmaceutical Biotechnology, Preclinical Molecular Pharmacology, Oncology
foto della persona

Maria Paola Turina

Assistant professor

keywords: ATP synthase, proton transport, electron tranfer, photosynthetic Reaction Center
foto della persona

Suleman Khan Zadran

Research fellow

keywords: Molecular biotechnology of phages- Development of theranostic vectors- Gene expression regulation in cancer- Molecular
foto della persona

Barbara Zambelli

Associate Professor

keywords: intrinsically disordered proteins, metal-homeostasis, urease, nickel, protein-protein interactions
foto della persona

Giampaolo Zuccheri

Assistant professor