Cancer biology

Development and application of cell and molecular biology, genetics, biochemistry and nanotechnology to understand tumorigenesis and tumor progression

Cancer is a highly heterogeneous disease stemming from normal cells acquiring aberrant features, such as hyperproliferation, immunoevasion and deregulated cellular energetics.

The research activities in Cancer Biology employ several approaches to investigate the causes of this aberrant acquisition, using experiments and approaches both computational, genetical and molecular. Further screening of cancer cells is performed using data acquisition of biochemical, metabolic and transcriptional features. This scope aims also at understanding the action of pathogenic organisms (viruses and bacteria) with oncogenic properties and, more in general, focuses on the identification of novel anti-cancer molecular targets and innovational therapeutic strategies.

People

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Monica Baiula

Junior assistant professor (fixed-term)

D cat. - technical, scientific and data processing area

Christian Bergamini

Associate Professor

keywords: Mitochondria, Mitochondrial electron transfer chain, Reactive Oxygen Species, Coenzyme Q10
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Dario De Biase

Senior assistant professor (fixed-term)

keywords: Molecular Pathology, Molecular alterations of solid tumors, Next Generation Sequencing, Tumors
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Concettina Cappadone

Assistant professor

keywords: magnesium, biomineralization, cancer, cell cycle, MDR
keywords: Bioinorganic Chemistry, Biomodelling, Biomolecular NMR spectroscopy, Metallo-chaperons, Urease, X-ray absorption
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Giovanna Farruggia

Assistant professor

keywords: fluorescece spectroscopy, flow cytometry, magnesium, fluorescent dye, cell proliferation
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Diana Fiorentini

Assistant professor

keywords: Antioxidants, Lipid rafts, Aquaporins, Redox signalling, NAD(P)H oxidase, Acute myeloid leukaemia, Glucose transport,
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Federico Manuel Giorgi

Associate Professor

keywords: Bioinformatics, Transcriptomics, Gene Networks, Plant Biology, Cancer Biology, Genomics, Biostatistics
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Luisa Iommarini

Senior assistant professor (fixed-term)

keywords: mitochondria, cancer, tumor, metabolism, hypoxia, oxidative phosphorylation
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Stefano Iotti

Full Professor

keywords: fluorescent dyes, Magnesium, Biosensors, hydroxyquinoline derivatives, Synchreotron-based x-ray microscopy, magnetic

Davide Maestri

PhD Student

Research fellow

Emil Malucelli

Associate Professor

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Daniele Mercatelli

Research fellow

Teaching tutor

keywords: Bioinformatics, Transcriptomics, Gene Networks, Genomics, Oncology, Biostatistics, Radiomics
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Francesco Musiani

Associate Professor

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Giovanna Picone

PhD Student

Teaching tutor

keywords: Cancer, multi-drug resistence, biomineralization, bone, magnesium
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Cecilia Prata

Assistant professor

keywords: Nutraceuticals, Signal transduction, NAD(P)H oxidases, Reactive Oxygen Species (ROS), Aquaporins, Antioxidants
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Francesco Rinaldi

PhD Student

Teaching tutor

keywords: RAD51, BRCA2, BRC4
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Manuela Sollazzo

Adjunct professor

Research fellow

Teaching tutor

keywords: cancer; metabolism; Respiratory Complex I; pro-tumorigenic signaling cascades; Drosophila melanogaster
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Roberto Tonelli

Assistant professor

keywords: Pharmaceutical Biotechnology, Preclinical Molecular Pharmacology, Oncology
keywords: Molecular biotechnology of phages- Development of theranostic vectors- Gene expression regulation in cancer- Molecular
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Barbara Zambelli

Assistant professor

keywords: intrinsically disordered proteins, metal-homeostasis, urease, nickel, protein-protein interactions
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Giampaolo Zuccheri

Assistant professor

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