Incontro "Summer school in Chemical And Genomics-Based Strategies In The Discovery Of Novel Drug Targets"
25 giugno - 3 luglio 2018
- In presenza : BOLOGNA 25 JUNE – 3 JULY 2018
- In italiano
Programma
CHEMICAL AND GENOMICS-BASED STRATEGIES
IN THE DISCOVERYOF NOVEL DRUG TARGETS
BOLOGNA 25 JUNE – 3 JULY 2018
SCHOOL DIRECTOR - PROF SANTI MARIO SPAMPINATO
Program
Monday,25 June
10,00-10,45 Registration
10,45-11,00 Opening Address
Santi Spampinato (Dept. Pharmacy and Biotechnology - University of Bologna)11,00-12,30
John M. Sedivy
(Department of Molecular Biology, Cell Biology and Biochemistry, Brown University, USA)
Opening lectureEpigenetic Changes and Somatic Retrotransposition in Cellular Senescence and Aging
Tuesday, 26 June
9,30-13,00 Laboratory practical experience
– Trasversal skills experiences Marco De Cecco14,30-15,45
Giorgio Spedicato (Dept. Pharmacy and Biotechnology - University of Bologna)Intellectual property and biotechnological innovation
15,45-16,00 Break
16,00-17,30
Marco De Cecco (Department of Molecular Biology, Cell Biology and Biochemistry, Brown University, USA)Cellular Senescence, inflammation and cell-intrinsic initiation of autoimmunity: new molecular paradigms in vitro and in vivo
Wednesday, 27 June
9,30-13,00 Laboratory practical experience
– Marco De Cecco14,30- 16,30
Round Table Pierluigi Martelli, John Sedivy, Andrea CavalliPerspective in drug discovery
16,30-16,45 Break
16,45-18,00
Jurgen Kraus (Department of Pharmacology and Toxicology, University of Magdeburg)Effects of opioids on immune functions
Thursday,28 June
9,30-10,45
Monica Baiula (Dept. Pharmacy and Biotechnology - University of Bologna)Integrins as therapeutic targets
10,45-11,00 Break
11,00-12,15
Andrea Bedini (Dept. Pharmacy and Biotechnology - University of Bologna)Biased agonism at GPCRs as a novel avenue for more effective and safer drugs: the paradigm of opioid receptors
INTERNATIONAL SUMMERSCHOOL PROGRAMME
14,30-16,00
Maurizio Crestani (University of Milano - School of Pharmacy)Genetic and epigenetic pathways in drug discovery (1): Nuclear receptors as pharmacological targets
16.00-16,15 Break
16,15-17,45
Maurizio Crestani (University of Milano - School of Pharmacy)Genetic and epigenetic pathways in drug discovery (2): Epigenetics of energy metabolism in diabetes
Friday, 29 June
9,30 -11,00
Catherine Lindon (Department of Pharmacology – University of Cambridge)Targets for drug development in ubiquitin-proteasome pathways
11,00-11,15 Break
11,15-12,45
Rita Morigi (Dept. Pharmacy and Biotechnology - University of Bologna)Targeting G-quadruplex structures: an attractive strategy for anticancer drug discovery
14,30-16,00
Nico Mitro (University of Milano - School of Pharmacy)Strategies to unravel, validate and confirm a novel mitochondrial regulator (Part I)
15,30-15,45 Break
15,45-17,00
Nico Mitro (University of Milano - School of Pharmacy)Strategies to unravel, validate and confirm a novel mitochondrial regulator (Part II)
Monday,2 July
9,30-13,00 Laboratory practical experience
- Trasversal skills experiences Monica Baiula-Andrea Bedini14,30-16,00
Andrea Banfi (Department of Biomedicine, Basel University Hospital)Therapeutic angiogenesis from vascular biology to regenerative medicine
16,00-16,15 Break
16,15-17,45
Milteny Biotech (Bologna)From biotechnology to cell & gene therapy: the history of a translational company
Tuesday, 3 July
9,30-13,00 Laboratory practical experience
- Monica Baiula-Andrea Bedini14,30-16,00
Maurizio Pellecchia (Center for Molecular and Translational Medicine UCR School of Medicine, Riverside USA)NMR- computer- and enthalpy-based design of novel potent covalent XIAP inhibitors
16,00-17,00 Written examination