Main Publications
-Sonia Bortolotti, Silvia Angelucci , Luca Montemurro, Damiano Bartolucci, Salvatore Raieli, Silvia Lampis, Camilla Amadesi, Annalisa Scardovi, Giammario Nieddu, Lucia Cerisoli, Francesca Paganelli, Francesca Chiarini, Gabriella Teti, Mirella Falconi, Andrea Pession, Patrizia Hrelia, Roberto Tonelli. Antigene MYCN Silencing by BGA002 Inhibits SCLC Progression Blocking mTOR Pathway and Overcomes Multidrug Resistance. Cancers (Basel). 2023 Feb 3;15(3):990. doi: 10.3390/cancers15030990.
- Damiano Bartolucci, Andrea Pession, Patrizia Hrelia, Roberto Tonelli. Precision anti-cancer medicines by oligonucleotide therapeutics targeting undruggable proteins and non-coding RNAs. Pharmaceutics. 2022 Jul 12;14(7):1453. doi: 10.3390/pharmaceutics14071453.
- Silvia Lampis, Salvatore Raieli, Luca Montemurro, Damiano Bartolucci, Camilla Amadesi, Sonia Bortolotti, Silvia Angelucci, Anna Lisa Scardovi, Giammario Nieddu, Lucia Cerisoli, Francesca Paganelli, Sabrina Valente, Matthias Fischer, Alberto Maria Martelli, Gianandrea Pasquinelli, Andrea Pession, Patrizia Hrelia, Roberto Tonelli. The MYCN inhibitor BGA002 restores the retinoic acid response leading to differentiation or apoptosis by the mTOR block in MYCN-amplified neuroblastoma. J Exp Clin Cancer Res. 2022 Apr 30;41(1):160. doi: 10.1186/s13046-022-02367-5.
- Salvatore Raieli, Daniele Di Renzo, Silvia Lampis, Camilla Amadesi, Luca Montemurro, Andrea Pession, Patrizia Hrelia, Matthias Fischer, Roberto Tonelli. MYCN drives a tumor immunosuppressive environment which impacts survival in Neuroblastoma. Front Oncol. 2021 Feb 25;11:625207. doi: 10.3389/fonc.2021.625207. eCollection 2021.
- Montemurro L, Raieli S, Angelucci S, Bartolucci D, Amadesi C, Lampis S, Scardovi AL, Venturelli L, Nieddu G, Cerisoli L, Fischer M, Teti G, Falconi M, Pession A, Hrelia P, Tonelli R. A novel MYCN-specific antigene oligonucleotide deregulates mitochondria and inhibits tumor growth in MYCN-amplified Neuroblastoma. Cancer Res. 2019 Dec 15;79(24):6166-6177. doi: 10.1158/0008-5472.CAN-19-0008. Epub 2019 Oct 15
Internship Projects
N.2 positions for thesis.